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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 861060생성일: 2026년 10월 26일

4-Methoxybenzylamine → 4-(3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[(4-methoxyphenyl)methyl]-2-pyrimidinamine

https://huagongshe.com/reaction/861060

반응식

참여 물질

역할이름HCID투입량
반응물4-MethoxybenzylamineHCID 75452—
반응물HCID 178505591HCID 178505591—
생성물4-(3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[(4-methoxyphenyl)methyl]-2-pyrimidinamineHCID 17849098280%

반응 단계

This compound was synthesized by refluxing 2-chloro-4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyrimidine prepared in accordance with Example A-299 in 4-methoxybenzylamine overnight. The product, 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[(4-methoxyphenyl)methyl]-2-pyrimidinamine, was obtained as a off-white solid in 80% yield, mp: 183–185° C.; Anal. Calc'd for C21H18FN5O: C, 67.19; H, 4.83; N, 18.66. Found: C, 67.01; H, 5.11; N, 18.93.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07153959B2
출처 데이터셋uspto-grants-2006_12
ORD IDord-471d3c339b9d4e3694c1629bd8873f1b
출처 메모uspto-grants-2006_12