Methyl tetrahydro-2,5-dimethoxyfuroate → HCID 19702952, 화합물

HRID 861479노트

반응식

HRID 861479 반응식
[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([NH:6][C:7](=[O:13])[C:8](=[O:12])[NH:9]2)=[CH:4][C:3]=1[Cl:14].[CH3:15][O:16][C:17]([C:19]1(OC)[CH2:23][CH2:22][CH:21](OC)O1)=[O:18]>C(O)(=O)C>[Cl:14][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:2]=1[N:1]1[CH:21]=[CH:22][CH:23]=[C:19]1[C:17]([O:16][CH3:15])=[O:18])[NH:9][C:8](=[O:12])[C:7](=[O:13])[NH:6]2

참가 물질

4

반응물 2

HCID 13152840Methyl tetrahydro-2,5-dimethoxyfuroateHCID 144236496-Amino-7-chloro-1,4-dihydro-2,3-quinoxalinedione

생성물 1

HCID 19702952HCID 19702952, 화합물수율 44%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

10 g (47.25 mmol) of 7-amino-6-chloro-2,3(1H,4H)-quinoxalinedione and 8.9 g (47.25 mmol) of 2-methoxycarbonyl-2,5-dimethoxytetrahydrofuran in 150 ml of acetic acid were refluxed for 2 h. The precipitate was then filtered off with suction to yield 6.6 g (44%) of the product. Melting point>260° C.

후처리

  1. filtrationThe precipitate was then filtered off with suction

출처 및 근거

ORD 기록
ord-b94c846d4c6a49bc8ebc1e46ae990d41
출처 데이터셋
uspto-grants-1998_02
특허 번호
US05714489

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