Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cornforth reagent → 5-Bromo-2-ethoxybenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cornforth reagent | HCID 2724130 | — |
| 반응물 | (5-Bromo-2-ethoxyphenyl)methanol | HCID 24721639 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 5-Bromo-2-ethoxybenzaldehyde | HCID 144901 | — |
반응 단계
5-Bromo-2-ethoxybenzyl alcohol (2.78 g, 12.0 mmol) and pyridinium dichromate (4.51 g, 12.0 mmol) in 120 ml of CH2Cl2 was stirred at RT for 6 h. The mixture was filtered, washed with H2O, 0.5N HCl and brine and dried over Na2SO4. The product was purified by silica gel column chromatography (EtOAc/petroleum ether 10:100) to give 5-bromo-2-ethoxybenzaldehyde.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05714503 |
| 출처 데이터셋 | uspto-grants-1998_02 |
| ORD ID | ord-14ed117b41fe4638a869c64991c7f68e |
| 출처 메모 | uspto-grants-1998_02 |