Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propargyl bromide → 1-(2-propynyl)1H-imidazo[4,5-c]quinolin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propargyl bromide | HCID 7842 | — |
| 반응물 | HCID 178508172 | HCID 178508172 | — |
| 생성물 | 1-(2-propynyl)1H-imidazo[4,5-c]quinolin-4-amine | HCID 15222808 | 15.8% |
반응 단계
Using the general method of Example 1, 2.1 g of 1H-imidazo[4,5-c]quinolin-4-amine was reacted with 1.7 g of propargyl bromide to provide 0.4 g of 1-(2-propynyl)-1H-imidazo[4,5-c]quinolin-4-amine, m.p. 220°-222° C. The structure was confirmed by nuclear magnetic resonance spectroscopy. Analysis: Calculated for C13H10N4 : %C, 70.3; %H, 4.5; %N, 25.2; Found: %C, 70.5; %H, 4.6; %N, 25.4.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05714608 |
| 출처 데이터셋 | uspto-grants-1998_02 |
| ORD ID | ord-f4e901de007d4123a7f01c90712f0f48 |
| 출처 메모 | uspto-grants-1998_02 |