Methane → HCID 131720463, 화합물

HRID 861996노트

반응식

HRID 861996 반응식
[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2].C.P(CC1C2N(C=C(C(O)=O)N=2)C=CC=1)(O)(O)=O.O1CCOCC1.[Cl:47]Cl>CCOCC>[ClH:47].[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2]

참가 물질

7

반응물 5

HCID 297MethaneHCID 24526ChlorineHCID 312751,4-DioxaneHCID 19701110Ethyl 5-(diethoxyphosphinyl)imidazo[1,2-a]pyridine-2-carboxylateHCID 19701381HCID 19701381, 화합물

생성물 1

HCID 131720463HCID 131720463, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

The product from Example 51 (1.6 g, 4.4 mmol) was dissolved in CH2 Cl2 (30 mL), treated with activated charcoal and filtered. To this filtrate was then added 6N HCl in dioxane (0.9 mL, 4.4 mmol) followed by Et2O (100 mL). The precipitated product was filtered, washed with Et2O, and dried in vacuo.

후처리

  1. filtrationfiltered
  2. filtrationThe precipitated product was filtered
  3. washwashed with Et2O
  4. customdried in vacuo

출처 및 근거

ORD 기록
ord-756be3881f944587ac22bb3e422c4239
출처 데이터셋
uspto-grants-1998_02
특허 번호
US05716964

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