Water → HCID 19697026, 화합물
반응식
[CH2:1]([C:4]1[NH:5][C:6]2[C:11]([C:12]=1[CH2:13][C:14]#N)=[CH:10][C:9]([O:16][CH3:17])=[CH:8][CH:7]=2)[CH:2]=[CH2:3].[OH2:18].[OH-:19].[K+]>C(O)(=O)C>[CH2:1]([C:4]1[NH:5][C:6]2[C:11]([C:12]=1[CH2:13][C:14]([OH:19])=[O:18])=[CH:10][C:9]([O:16][CH3:17])=[CH:8][CH:7]=2)[CH:2]=[CH2:3]참가 물질
5
실험 절차
0.08 mole of 2-allyl-5-methoxy-3-indolyl acetonitrile is added to a mixture of 140 ml. of alcohol, 100 ml. of water and 4.3 g. of KOH. The mixture is refluxed 15 hours and then brought to room temperature. Glacial acetic acid (60 ml.) is added, and the solution is filtered through a talc filter. The filtrate is diluted with 500 ml. of water, and the precipitated 2-allyl-5-methoxy-3-indolyl acetic acid is separated by filtration and dried.
후처리
- temperatureThe mixture is refluxed 15 hours
- custombrought to room temperature
- filtrationthe solution is filtered through a talc
- filtrationfilter
- additionThe filtrate is diluted with 500 ml
- customof water, and the precipitated 2-allyl-5-methoxy-3-indolyl acetic acid is separated by filtration
- customdried
출처 및 근거
- ORD 기록
- ord-1639a2790b3f463380935713ab0230ab
- 출처 데이터셋
- uspto-grants-1998_02
- 특허 번호
- US05721347
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