Imidazole → Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
반응식
[OH:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].N1C=CN=C1.[Si:15](Cl)([C:18]([CH3:21])([CH3:20])[CH3:19])([CH3:17])[CH3:16]>CN(C=O)C>[Si:15]([O:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5])([C:18]([CH3:21])([CH3:20])[CH3:19])([CH3:17])[CH3:16]참가 물질
5
실험 절차
A solution of 2-hydroxybenzaldehyde (500 mg, 0.44 ml, 4.09 mmol), imidazole (685 mg) and tert-butyldimethylsilyl chloride (680 mg) in DMF is stirred for 24 hours at room temperature. After hydrolysis and customary extraction, chromatography gives 28 (890 mg, 93%).
후처리
- customAfter hydrolysis and customary extraction, chromatography
출처 및 근거
- ORD 기록
- ord-aa289e50a0f44146b6049ebd2c54f19c
- 출처 데이터셋
- uspto-grants-1996_10
- 특허 번호
- US05561119
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