Potassium Hydroxide → HCID 19418871, 화합물

반응식

[Br:1][C:2]1[C:3]([O:15][CH3:16])=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([C:11]([O:13]C)=[O:12])=[CH:7]2.[OH-].[K+]>>[Br:1][C:2]1[C:3]([O:15][CH3:16])=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([C:11]([OH:13])=[O:12])=[CH:7]2

참가 물질

반응물 2

HCID 14797Potassium Hydroxide

HCID 16726759Methyl 7-bromo-6-methoxy-1H-indole-2-carboxylate

생성물 1

HCID 19418871HCID 19418871, 화합물

실험 절차

Following the general procedure of PREPARATION 63 and making non-critical variations but starting with methyl 7-bromo-6-methoxyindole carboxylate (PREPARATION 81, 0.36 g) and potassium hydroxide (0.11 g), the title compound is obtained, NMR (300 MHz, CD3OD) 7.58, 7.20, 6.96 and 3.93 δ.

후처리

customthe general procedure of PREPARATION 63

출처 및 근거

ORD 기록: ord-278a6ce31b3c47f389071bfab420b31d
출처 데이터셋: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05563142

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