Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nimetazepam → Nordiazepam
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nimetazepam | HCID 4496 | — |
| 반응물 | Nitrazepam | HCID 4506 | — |
| 반응물 | 1,3-dihydro-5-(4-methoxyphenyl)-2H-1,4-benzodiazepin-2-one | HCID 15162777 | — |
| 반응물 | 1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one | HCID 19078731 | — |
| 반응물 | 1,3-dihydro-5-(4-methoxyphenyl)-3-(4-hydroxyphenyl)-2H-1,4-benzodiazepin-2-one | HCID 19078739 | — |
| 반응물 | 1,3-dihydro-5-(2-thienyl)-2H-1,4-benzodiazepin-2-one | HCID 19078745 | — |
| 반응물 | 7-chloro-1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one | HCID 19078775 | — |
| 반응물 | 1,3-dihydro-1-isopropyl-6-methyl-2H-1,4-benzodiazepin-2-one | HCID 19078788 | — |
| 반응물 | 5-cyclohexyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one | HCID 135476124 | — |
| 생성물 | Nordiazepam | HCID 2997 | — |
반응 단계
1,3-dihydro-5-(4-methoxyphenyl)-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-1-isopropyl-6-methyl-2H-1,4-benzodiazepin-2-one; 7-nitro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; 5-cyclohexyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-5-(2-thienyl)-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-chloro-1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-5-(4-methoxyphenyl)-3-(4-hydroxyphenyl)-2H-1,4-benzodiazepin-2-one;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05567391 |
| 출처 데이터셋 | uspto-grants-1996_10 |
| ORD ID | ord-65ebe607ab504fa395b915dda369c43d |
| 출처 메모 | uspto-grants-1996_10 |