참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Tobramycin Sulphate Salt | HCID 62005 | — |
| 반응물 | Traumatic Acid | HCID 5283028 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Tobramycin trans-traumatate | HCID 131719627 | — |
반응 단계
11.4 g of trans-traumatic traumatic acid (50 mmol) are suspended in 200 ml of cool water at 4° C., A solution of 14.3 g of tobramycin sulfate (20mmol) in 200 ml of water is eluted through a column cooled to 4° C. containing 150 ml of [OH--] Dowex 1×8 resin. The eluate free from sulfate is collected into the suspension of traumatic acid kept under continuous stirring at 4° C. The resulting solution is frozen and lyophilized.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05567716 |
|---|
| 출처 데이터셋 | uspto-grants-1996_10 |
|---|
| ORD ID | ord-0a400e07c9f64a6c93bccec9c523a1ca |
|---|
| 출처 메모 | uspto-grants-1996_10 |
|---|
