Traumatic Acid → HCID 178512160, 화합물

HRID 865830

반응식

HRID 865830 반응식
[C:1]([OH:16])(=[O:15])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13].O.C(O)C.[CH:21]1[C:26]([NH:27]/[C:28](/[NH2:53])=[N:29]/[C:30]([NH2:52])=[N:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][N:38]=[C:39](/[N:41]=[C:42](\[NH:44][C:45]2[CH:50]=[CH:49][C:48]([Cl:51])=[CH:47][CH:46]=2)/[NH2:43])[NH2:40])=[CH:25][CH:24]=[C:23]([Cl:54])[CH:22]=1>O>[CH:46]1[C:45]([NH:44][C:42]([NH:41][C:39]([NH:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][NH:31][C:30]([NH:29][C:28]([NH:27][C:26]2[CH:21]=[CH:22][C:23]([Cl:54])=[CH:24][CH:25]=2)=[NH:53])=[NH:52])=[NH:40])=[NH:43])=[CH:50][CH:49]=[C:48]([Cl:51])[CH:47]=1.[C:1]([O-:16])(=[O:15])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([O-:14])=[O:13]

참가 물질

5

반응물 3

HCID 5283028Traumatic AcidHCID 5360566(1E)-2-[6-[[amino-[(Z)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidineHCID 19096565Water ethanol

생성물 1

HCID 178512160HCID 178512160, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
4 °C

실험 절차

2,28 g of trans-traumatic acid (10 mmol) are suspended in 100 ml of a mixture water/ethanol 2: 1 at 4° C., 5,05 g of chlorhexidine base (10 mmol) are added and the mixture is kept under stirring at 4° C. for hours and then at 25° C. overnight. 200 ml of water are added and the mixture is concentrated under vacuum at the volume of about 100 ml and Finally again cooled to 4° C. The resulting precipitate is recovered by filtration, washed three times using 10 ml of cool water and finally dried under high vacuum.

후처리

  1. customat 25° C.
  2. customovernight
  3. concentrationthe mixture is concentrated under vacuum at the volume of about 100 ml
  4. temperatureFinally again cooled to 4° C
  5. filtrationThe resulting precipitate is recovered by filtration
  6. washwashed three times
  7. customfinally dried under high vacuum

출처 및 근거

ORD 기록
ord-0b32a9ea0887407ca1fdee8303d5a98d
출처 데이터셋
uspto-grants-1996_10
특허 번호
US05567716

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