Dichloromethane → HCID 19047584, 화합물

HRID 865973노트

반응식

HRID 865973 반응식
[O:1]1[CH:5]=[CH:4][C:3]([C:6](=O)[CH2:7]C)=[CH:2]1.[C:10](=[O:13])([O-])[O-].[K+].[K+].[CH2:16](Cl)Cl>C1(C)C=CC(S(O)(=O)=O)=CC=1>[O:1]1[CH:5]=[CH:4][C:3]([C:6]([O:13][CH2:10][CH3:16])=[CH2:7])=[CH:2]1

참가 물질

5

반응물 3

HCID 6344DichloromethaneHCID 11430Potassium CarbonateHCID 150538531-(3-Furanyl)-1-propanone

생성물 1

HCID 19047584HCID 19047584, 화합물수율 29%

시약·촉매·용매 1

HCID 6101p-Toluenesulfonic acid촉매

실험 절차

To a stirring mixture of 1-(3-furyl)-1-propanone (6.75 g, 0.0612 mol) in 150 ml of methylene chloride was added TEOF (13.2 ml, 0.079 mol) with stirring followed by 100 mg of p-toluenesulfonic acid and the resulting mixture was stirred for 126 h. Potassium carbonate (2 g) was added to the above reaction mixture, stirred for 10 min, filtered, and concentrated in vacuo. The residue was distilled (35 mm, 82°-85° C.) to afford 2.5 g of (29%) 1-(3-furyl)-1-ethoxy-ethylene (Formula III: R2 =R3 =H;R4 =CH3CH2O;R5 =3-furanyl), as a clear oil.

후처리

  1. additionwas added TEOF (13.2 ml, 0.079 mol)
  2. stirringthe resulting mixture was stirred for 126 h
  3. stirringstirred for 10 min
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo
  6. distillationThe residue was distilled (35 mm, 82°-85° C.)

출처 및 근거

ORD 기록
ord-df24476fd8074a638f40fa515d7d73c6
출처 데이터셋
uspto-grants-1996_10
특허 번호
US05569655

반응 노트

불러오는 중…