Ethanol → Ethyl 2-hydroxy-2-phenylpropanoate

HRID 866002

반응식

HRID 866002 반응식
[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH2:18](O)[CH3:19]>CCOCC>[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([O:10][CH2:18][CH3:19])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 1303Atrolactic acid

생성물 1

HCID 6429709Ethyl 2-hydroxy-2-phenylpropanoate

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

(±)-Phenyllactic acid (4.96 g) and 1/2 ml concentrated sulfuric acid in 150 ml absolute ethanol is refluxed for 18 hours. Solvent is stripped, the residue is dissolved in ether, and extracted with saturated sodium bicarbonate solution. The ether is dried, filtered, and stripped to leave (±)-ethyl phenyllactate. NMR (CDCl3): δ1.3 (t, 3H), 3.0(d of d, 1H), 3.1 (d of d, 1H), 4.2 (q, 2H), 4.4 (d of d, 1H), 7.3 (m, 5H).

후처리

  1. extractionextracted with saturated sodium bicarbonate solution
  2. dry with materialThe ether is dried
  3. filtrationfiltered

출처 및 근거

ORD 기록
ord-4da8ca9e64d34f87bdf406815196a29d
출처 데이터셋
uspto-grants-1996_10
특허 번호
US05569674

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