Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 2-(Bromomethyl)-1,3-dimethoxybenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | Sodium Chloride | HCID 5234 | — |
| 반응물 | (2,6-Dimethoxyphenyl)methanol | HCID 2776839 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-(Bromomethyl)-1,3-dimethoxybenzene | HCID 15556958 | — |
반응 단계
After a mixture of 5.7 grams (0.034 mole) of 2,6-dimethoxyphenylmethanol in 40 mL of concentrated hydrobromic acid was stirred at ambient temperature for about one hour, the reaction mixture was taken up in diethyl ether. Solid sodium chloride was added to the mixture to obtain a phase separation. The organic layer was separated and concentrated under reduced pressure, yielding about 4.7 grams of 2,6-dimethoxyphenylmethyl bromide. This compound was used immediately in the next reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05569664 |
| 출처 데이터셋 | uspto-grants-1996_10 |
| ORD ID | ord-7323ba6f5da0405a87601d1bbdbdb171 |
| 출처 메모 | uspto-grants-1996_10 |