Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → [2-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-thiophen-3-yl-methylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-methylthiophen-3-amine | HCID 642344 | — |
| 반응물 | 3-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole | HCID 21983582 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | [2-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-thiophen-3-yl-methylamine | HCID 69652881 | — |
반응 단계
The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, thiophen-3-yl-methylamine (prepared according to Synthetic Metals, 26 (1988)153–168) and acetonitrile essentially as described above in example 18, except that water (0.40 mL) is added to the reaction mixture before heating. Purity by LC/MS (APCI)=100%, [M+H]+=357.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091199B1 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-9c632d1f03ef4ea1ad693653be4afc16 |
| 출처 메모 | uspto-grants-2006_08 |