Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(N,N-dibenzylglycyl)-o-anisamide → 5-(2-Amino-1-hydroxyethyl)-o-anisamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(N,N-dibenzylglycyl)-o-anisamide | HCID 20318584 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-(2-Amino-1-hydroxyethyl)-o-anisamide | HCID 20318583 | — |
반응 단계
A solution of 5-(N,N-dibenzylglycyl)-o-anisamide (3.88g) in tetrahydrofuran (25 ml) and ethanol (125ml) was added to a pre-reduced suspension of 10% Pd/C (1.0g) in ethanol (25 ml). Uptake of hydrogen ceased within 14 hours. The catalyst was filtered off and the solvent evaporated under reduced pressure to leave 5-(2-amino-1-hydroxyethyl)-o-anisamide as a colourless gum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04101579 |
| 출처 데이터셋 | uspto-grants-1978_07 |
| ORD ID | ord-4f0d162cc99e46d8bdd5aa4995cc500b |
| 출처 메모 | uspto-grants-1978_07 |