Methyl 7-[2-(3-acetyloxyoctyl)-4-oxo-3-thiazolidinyl]heptanoate → 7-{2-[2-(Tetrahydro-2H-pyran-2-yl)-ethyl]-4-oxo-3-thiazolidinyl}heptanoic Acid
반응식
C([O:4][CH:5]([CH2:24][CH2:25][CH2:26][CH2:27]C)[CH2:6][CH2:7][CH:8]1[N:12]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21]C)=[O:20])[C:11](=[O:23])[CH2:10][S:9]1)(=O)C.O1CCCCC1CCC1N(CCCCCCC(OC)=O)C(=O)CS1>>[O:4]1[CH2:27][CH2:26][CH2:25][CH2:24][CH:5]1[CH2:6][CH2:7][CH:8]1[N:12]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=[O:20])[C:11](=[O:23])[CH2:10][S:9]1참가 물질
3
실험 절차
This compound is prepared essentially by the method as described in Example 1, Step B, except that the methyl 7-[2-(3-acetyloxyoctyl)-4-oxo-3-thiazolidinyl]heptanoate is replaced by methyl 7-{2-[2-(tetrahydro-2H-pyran-2-yl)ethyl]-4-oxo-3-thiazolidinyl}heptanoate. After chromatographic purification on silica gel, the title compound is obtained as a viscous, pale yellow oil.
후처리
- customThis compound is prepared essentially by the method