Acetic Acid → 4-[(1E)-3-(Acetyloxy)-1-propen-1-yl]-2-methoxyphenol

HRID 867165노트

반응식

HRID 867165 반응식
C([O:4][C:5]1[C:6]([O:14][CH3:15])=[CH:7][C:8]([CH2:11][CH:12]=[CH2:13])=[CH:9][CH:10]=1)(=O)C.[C:16]([OH:19])(=[O:18])[CH3:17]>>[C:16]([O:19][CH2:13]/[CH:12]=[CH:11]/[C:8]1[CH:9]=[CH:10][C:5]([OH:4])=[C:6]([O:14][CH3:15])[CH:7]=1)(=[O:18])[CH3:17]

참가 물질

3

반응물 2

HCID 176Acetic AcidHCID 7136Eugenyl Acetate

생성물 1

HCID 128354304-[(1E)-3-(Acetyloxy)-1-propen-1-yl]-2-methoxyphenol

실험 절차

A mixture of eugenol acetate (16 g,0.0777 mol) and mercuric acetate (44.5 g, 1.4 mol) in 160 ml of acetic acid was refluxed for 20 hr. After filtration, the acetic acid solution was poured into water (150 ml) and extracted with ether (200 ml). The etheral solution was washed successively with water, aqueous NaHCO3, saturated NaCl solution and dried (Na2SO4). The solvent was evaporated to give 18 g of coniferyl acetate. Subsequent reduction of the coniferyl acetate with Red-Al gave coniferyl alcohol.

후처리

  1. temperaturewas refluxed for 20 hr
  2. filtrationAfter filtration
  3. additionthe acetic acid solution was poured into water (150 ml)
  4. extractionextracted with ether (200 ml)
  5. washThe etheral solution was washed successively with water, aqueous NaHCO3, saturated NaCl solution
  6. dry with materialdried (Na2SO4)
  7. customThe solvent was evaporated

출처 및 근거

ORD 기록
ord-7444acb56e3146819047587fbf5339b9
출처 데이터셋
uspto-grants-1978_07
특허 번호
US04103006

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