Potassium Carbonate → Indan-1-yl-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl)-amine

HRID 8677

반응식

HRID 8677 반응식
Br[CH2:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]([C:11]2[C:15]3[S:16][CH:17]=[CH:18][C:14]=3[O:13][N:12]=2)[CH:8]=[CH:9][CH:10]=1.C(=O)([O-])[O-].[K+].[K+].[NH2:25][CH:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27]1>C(#N)C>[CH:26]1([NH:25][CH2:2][CH2:3][O:4][C:5]2[CH:10]=[CH:9][CH:8]=[C:7]([C:11]3[C:15]4[S:16][CH:17]=[CH:18][C:14]=4[O:13][N:12]=3)[CH:6]=2)[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27]1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 123445(+-)-1-AminoindanHCID 219835823-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

생성물 1

HCID 23548230Indan-1-yl-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl)-amine

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

The title compound is prepared from 3-[3-(2-bromo-ethoxy]phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 1-aminoindan and acetonitrile essentially as described above in example 35. Purity by LC/MS (APCI)=99%, [M+H]+=377.

출처 및 근거

ORD 기록
ord-e25271e79aec4857a9780483483882d6
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091199B1

연결된 노트

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