Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Phenylpiperazine → 3-{3-[2-(4-Phenyl-piperazin-1-yl)-ethoxy]-phenyl}-thieno[2,3-d]isoxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Phenylpiperazine | HCID 7096 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole | HCID 21983582 | — |
| 생성물 | 3-{3-[2-(4-Phenyl-piperazin-1-yl)-ethoxy]-phenyl}-thieno[2,3-d]isoxazole | HCID 21983595 | 66% |
반응 단계
The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, and N-phenylpiperazine essentially as described in example 27 except that the freebase is dried to give the title compound (330 mg, 66%). Mp=91–93° C. Microanalysis (C, H, N) is consistent with the final compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091199B1 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-7a208bef3d67408193e3c036ee51db44 |
| 출처 메모 | uspto-grants-2006_08 |