m-Chloroperbenzoic acid → HCID 178526259, 화합물

HRID 868500노트

반응식

HRID 868500 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12.ClC1C=CC=C(C(OO)=[O:19])C=1>C(O)(=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][N+:5]([O-:19])=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 178478247HCID 178478247, 화합물

생성물 1

HCID 178526259HCID 178526259, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

7-Chloro-3H-imidazo[4,5-b]pyridine (15 g, 97.7 mMol) was dissolved in 150 mL of glacial acetic acid and m-chloroperbenzoic acid (23 g, 131 mMol) was added in portions to the stirred solution. After 12 hours the solid was isolated and washed with ether. The solid was suspended in 400 mL of hot ethanol, stirred, and isolated. The product, 7-chloro-3H-imidazo[4,5-b]pyridine-4-oxide, was dried in vacuo. Yield 14.98 g (8.83 mMol, 90.4%); m.p. 200° C. (dec).

후처리

  1. customAfter 12 hours the solid was isolated
  2. washwashed with ether
  3. customisolated
  4. dry with materialThe product, 7-chloro-3H-imidazo[4,5-b]pyridine-4-oxide, was dried in vacuo

출처 및 근거

ORD 기록
ord-0a56a881bad44beea6cc96d5ffe81037
출처 데이터셋
uspto-grants-1988_10
특허 번호
US04780452

반응 노트

불러오는 중…