Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 7-Hydroxyisoflavone | HCID 5376891 | — |
| 반응물 | 3-Chloro-N,N-dimethyl-3-phenylpropan-1-amine | HCID 12707239 | — |
| 촉매 | Benzyl triethylammonium chloride | HCID 66133 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone | HCID 12918914 | — |
반응 단계
200 ml of 50% aqueous sodium hydroxide solution and 1 g of triethylbenzylammonium chloride are added to a solution of 23.8 g of 7-hydroxyisoflavone in 100 ml of CH2Cl2, 20 g of 1-chloro-1-phenyl-3-dimethylaminopropane is added dropwise while stirring and stirring is continued for a further hour. Working up in the customary manner gives 7-(1-phenyl-3-dimethylaminopropoxy)-isoflavone. M.p. 128°-130°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04780478 |
| 출처 데이터셋 | uspto-grants-1988_10 |
| ORD ID | ord-b0358f963c294462a6e573785cc0d55e |
| 출처 메모 | uspto-grants-1988_10 |