Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quipazine → 8-[3-(4-Quinolin-2-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quipazine | HCID 5011 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 8-(3-Bromopropyloxy)-8-azaspiro[4.5]decan-7,9-dione | HCID 14280583 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 8-[3-(4-Quinolin-2-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione | HCID 14280594 | — |
반응 단계
A mixture of 8-(3-bromopropyloxy)-8-azaspiro[4.5]decan-7,9-dione (5.7 g), 1-(2-quinolinyl)piperazine (4.0 g) and diisopropylethylamine (6.6 ml) in 100 ml of dry CH3CN was heated to 80° with stirring under N2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04780466 |
| 출처 데이터셋 | uspto-grants-1988_10 |
| ORD ID | ord-f72222369e624ba7bdf606f5901df12b |
| 출처 메모 | uspto-grants-1988_10 |