Semicarbazide hydrochloride → HCID 178422414, 화합물

HRID 868603노트

반응식

HRID 868603 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH3:22])[CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][N:13]([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])[C:8](=[O:20])[C:7]2=O.Cl.[NH2:24][NH:25][C:26]([NH2:28])=[O:27]>>[Br:1][C:2]1[CH:3]=[C:4]([CH3:22])[CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][N:13]([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])[C:8](=[O:20])/[C:7]/2=[N:24]/[NH:25][C:26]([NH2:28])=[O:27]

참가 물질

3

반응물 2

HCID 11236Semicarbazide hydrochlorideHCID 13934419HCID 13934419, 화합물

생성물 1

HCID 178422414HCID 178422414, 화합물수율 87.9%

실험 절차

By using 7-bromo-1-(2-diisopropylaminoethyl)-5-methylisatin and semicarbazide hydrochloride, a method analogous to that described in Example 4 was carried out to obtain (E)-7-bromo-1-(2-diisopropylaminoethyl)-5-methylisatin 3-semicarbazone having a melting point of 189°-192° C. (yield: 87.9%, recrystallizing solvent: chloroform-hexane)

출처 및 근거

ORD 기록
ord-7fa56d7f977b4dfa9596d1a74cec2539
출처 데이터셋
uspto-grants-1988_10
특허 번호
US04780477

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