Water → 6-Methylbenzofuran

HRID 868612노트

반응식

HRID 868612 반응식
S(=O)(=O)(O)O.O[CH:7]1[C:11]2[CH:12]=[CH:13][C:14]([CH3:16])=[CH:15][C:10]=2[O:9][CH2:8]1.O>C1C=CC=CC=1>[CH3:16][C:14]1[CH:13]=[CH:12][C:11]2[CH:7]=[CH:8][O:9][C:10]=2[CH:15]=1

참가 물질

5

반응물 3

HCID 962Water2회HCID 1118Sulfuric AcidHCID 13013062HCID 13013062, 화합물

생성물 1

HCID 869296-Methylbenzofuran

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

Sulfuric acid (0.2 ml) and 10.0 g of 3-hydroxy-6-methyl-2,3-dihydrobenzofuran were dissolved in 200 ml of benzene and heated at reflux with the azeotropic removal of water. After 3 hours, the reaction mixture was added to water (500 ml) and extracted with ether. The combined ether extracts were washed with water and saturated aqueous sodium bicarbonate, dried with sodium sulfate and the solvent evaporated to give 6-methylbenzofuran.

후처리

  1. temperatureheated
  2. extractionextracted with ether
  3. washThe combined ether extracts were washed with water and saturated aqueous sodium bicarbonate
  4. dry with materialdried with sodium sulfate
  5. customthe solvent evaporated

출처 및 근거

ORD 기록
ord-aa59cb39a31b47429db72de6c2e5170b
출처 데이터셋
uspto-grants-1988_10
특허 번호
US04780480

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