Indole-2-carboxylic acid → HCID 178470236, 화합물
반응식
N1[CH2:5][CH2:4][CH:3]([CH2:6][O:7][C:8]2[C:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[N:10][CH:11]=[CH:12][CH:13]=2)C1.[F:19][C:20]([F:31])([F:30])[C@H:21]1[CH2:26][CH2:25][C@H:24]([C:27](O)=[O:28])[CH2:23][CH2:22]1.[NH:32]1C2C(=CC=CC=2)C=[C:33]1C(O)=O>>[F:19][C:20]([F:31])([F:30])[C@H:21]1[CH2:26][CH2:25][C@H:24]([C:27]([N:32]2[CH2:33][CH2:5][CH2:4][CH:3]2[CH2:6][O:7][C:8]2[C:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[N:10][CH:11]=[CH:12][CH:13]=2)=[O:28])[CH2:23][CH2:22]1참가 물질
4
실험 절차
The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 1 using ethyl 3-(pyrrolidin-3-ylmethoxy)picolinate (EXAMPLE 92, Step 2) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride and indole-2-carboxylic acid.
출처 및 근거
- ORD 기록
- ord-7c40f4c62b24445b9b57ea3cb9bd5d29
- 출처 데이터셋