Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 5-(2-methoxyethoxy)-2-nitrobenzoate → Methyl 2-amino-5-(2-methoxyethoxy)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 5-(2-methoxyethoxy)-2-nitrobenzoate | HCID 66639151 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 2-amino-5-(2-methoxyethoxy)benzoate | HCID 61305437 | 100% |
반응 단계
To methyl 5-(2-methoxyethoxy)-2-nitrobenzoate (1.08 g, 4.2 mmol) under argon was added 10% Palladium on carbon and MeOH (20 mL). The flask was flushed with H2(g) and stirred under H2 (1 atm) for 30 minutes. The mixture was filtered through Celite and concentrated in vacuo to give methyl 2-amino-5-(2-methoxyethoxy)benzoate (964 mg, 4.2 mmol, 100%). LC-MS (ESI) m/z 226 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08969587B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-5a303abe4bb545b3854203e5b8f94033 |
| 출처 메모 | uspto-grants-2015_03 |