Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Cyclohexylimidazo[1,5-a]pyrazine → 3-cyclohexyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Cyclohexylimidazo[1,5-a]pyrazine | HCID 21983665 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-cyclohexyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine | HCID 21983608 | 87.5% |
반응 단계
A solution of 3-cyclohexyl-imidazo[1,5-a]pyrazine 8a (960 mg, 4.4 mmol) in 25 ml ethanol was treated with 100 mg Adam's catalyst and stirred vigorously under one atmosphere of hydrogen for 18 hr. The mixture was filtered through a pad of Celite®. The filtrate was concentrated in vacuo to yield 790 mg of 3-cyclohexyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine 9a as a greenish-yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091200B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-2c854fda8c814904b2a39cc1640404a8 |
| 출처 메모 | uspto-grants-2006_08 |