2-Bromopropane → 2-Iodo-8-isopropoxyquinoline

반응식

[I:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[C:5]([OH:12])[CH:6]=[CH:7][CH:8]=2)[N:3]=1.Br[CH:14]([CH3:16])[CH3:15]>>[I:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[C:5]([O:12][CH:14]([CH3:16])[CH3:15])[CH:6]=[CH:7][CH:8]=2)[N:3]=1

참가 물질

반응물 2

HCID 63582-Bromopropane

HCID 211635362-Iodoquinolin-8-ol

생성물 1

HCID 579393102-Iodo-8-isopropoxyquinoline수율 84%

실험 절차

Reaction of 2-iodo-quinolin-8-ol 8 with 2-bromopropane following the method described in Example 8 gave 2-iodo-8-isopropoxyquinoline 9 in 84% yield. 9:

출처 및 근거

ORD 기록: ord-38723f1465dd450cbde137c14d46f1a2
출처 데이터셋: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08975278B2

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