참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Lawesson's reagent | HCID 87949 | — |
| 반응물 | 2-(Tertbutyldiphenylsilyloxy)propanamide | HCID 67168528 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(Tert-butyldiphenylsilyloxy)propanethioamide | HCID 87294964 | — |
반응 단계
A flask containing 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide (387 mg, 0.957 mmol) was put under nitrogen atmosphere. 2-(tert-butyldiphenylsilyloxy)propanamide (622 mg, 1.899 mmol) dissolved in dry THF (10 ml) was added, temperature was raised to 60° C. and the mixture was allowed to react for 3 h. The solvent was evaporated and the product was extracted from DCM/water. The product was used in the next step without further purification. LC-MS: [M+1]=344.56.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08975254B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_03 |
|---|
| ORD ID | ord-55ce6e08d68e4ee2846797447671d860 |
|---|
| 출처 메모 | uspto-grants-2015_03 |
|---|
