3,4-Difluorobenzaldehyde → 4-((6-Chloropyridin-3-yl)oxy)-3-fluorobenzaldehyde

반응식

[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1F)[CH:5]=[O:6].[Cl:11][C:12]1[N:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[N:17]=[CH:16][C:15]([O:18][C:9]2[CH:8]=[CH:7][C:4]([CH:5]=[O:6])=[CH:3][C:2]=2[F:1])=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 5880883,4-Difluorobenzaldehyde

HCID 8198212-Chloro-5-hydroxypyridine

생성물 1

HCID 867241924-((6-Chloropyridin-3-yl)oxy)-3-fluorobenzaldehyde

실험 절차

The title compound was prepared by a procedure similar to that described for D4 starting from 3,4-difluorobenzaldehyde and 6-chloropyridin-3-ol.

출처 및 근거

ORD 기록: ord-027d2e70e7574ad989ed02b90cc2d9eb
출처 데이터셋: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08975400B2

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