Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2S,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate → Methyl 2-((benzoylamino)methyl)-3-oxobutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2S,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate | HCID 10060699 | — |
| 반응물 | (2R,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate | HCID 10399905 | — |
| 생성물 | Methyl 2-((benzoylamino)methyl)-3-oxobutanoate | HCID 11831808 | — |
반응 단계
The ADH-LK variant with SEQ ID No. 90 was used for further evolution of an efficient KRED for production of (2S,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate. Similarly, an ADH-LK variant with SEQ ID No.94 containing 10 mutations compared to ADH-LK which gave primarily the (2R,3R) stereoisomer, was used for further evolution of an efficient KRED for production of (2R,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08980606B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-624b4080a11c4acd9ec352edac3272ec |
| 출처 메모 | uspto-grants-2015_03 |