Benzyl Bromide → HCID 86655187, 화합물

HRID 874172노트

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HRID 874172 반응식
[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH3:18])[C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:19]([Br:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>C1(C)C=CC=CC=1>[Br-:26].[CH2:19]([N:8]1[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:11]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[N+:10]([CH3:18])=[CH:9]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

4

반응물 2

HCID 7498Benzyl BromideHCID 129747981-Methyl-4,5-diphenyl-1H-imidazole

생성물 1

HCID 86655187HCID 86655187, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

In a 25 ml one-necked flask, there is dissolved 0.240 g (1.024 mmol) of 4,5-diphenyl-1-methylimidazole, which was obtained according to Zeitschrift fuer Naturforschung, B: Chemical Sciences (2003), 58(4), 305-310, in 10 ml of toluene and then 183 μl (1.536 mmol) of benzyl bromide are added. After 2 days of heating under reflux, the reaction medium is concentrated under reduced pressure. The residue is taken up in 50 ml of diisopropyl ether. The precipitate formed is drained, washed twice with 5 ml of diisopropyl ether and then dried under reduced pressure. There is thus obtained 0.480 g (100%) of 3-benzyl-4,5-diphenyl-1-methylimidazolium bromide, in the form of a yellow solid, used as it is in the next step, whose characteristic is the following:

후처리

  1. customwhich was obtained
  2. temperatureAfter 2 days of heating
  3. temperatureunder reflux
  4. concentrationthe reaction medium is concentrated under reduced pressure
  5. customThe precipitate formed
  6. washwashed twice with 5 ml of diisopropyl ether
  7. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-339b94affe63437897c82b92d8d5b3b4
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08980875B2

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