Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 874689생성일: 2026년 10월 26일
tert-Butoxy bis(dimethylamino)methane → (E)-6-(bis(4-methoxybenzyl)amino)-4-(2-(dimethylamino)vinyl)nicotinonitrile
https://huagongshe.com/reaction/874689
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| 반응물 | 6-(Bis(4-methoxybenzyl)amino)-4-methylnicotinonitrile | HCID 117666052 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (E)-6-(bis(4-methoxybenzyl)amino)-4-(2-(dimethylamino)vinyl)nicotinonitrile | HCID 89525377 | 113.7% |
반응 단계
A mixture of 4-3 (7.20 g, 19.3 mmol), tert-butoxy bis(dimethylamino)methane (16.0 mL, 77.5 mmol), and N,N-dimethylformamide (5.40 mL) was stirred at 70° C. for 16 hours under an atmosphere of nitrogen gas. The reaction mixture was concentrated under reduced pressure to give 9.40 g of 4-4 as a brown oil. The crude product was used for next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08980916B2 |
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| 출처 데이터셋 | uspto-grants-2015_03 |
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| ORD ID | ord-7308b08ea5f341f3a4a2a44cbb67045a |
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| 출처 메모 | uspto-grants-2015_03 |
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