2-Chloro-6-fluorobenzoyl chloride → N-[3-(2-chloro-6-fluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide

반응식

[NH:1]1[C:5]2=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:14][C:15]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:16]=1[C:17](Cl)=[O:18]>>[Cl:14][C:15]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:16]=1[C:17]([C:3]1[C:4]2[C:5](=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=2)[NH:1][CH:2]=1)=[O:18]

참가 물질

반응물 2

HCID 27365472-Chloro-6-fluorobenzoyl chloride

HCID 86720620N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide

생성물 1

HCID 71618238N-[3-(2-chloro-6-fluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide

실험 절차

N-[3-(2-Chloro-6-fluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide was prepared analogously using N-(1H-pyrrolo[2,3-c]pyridin-7-yl) acetamide and 2-chloro-6-fluoro benzoyl chloride (Compound No. 8).

출처 및 근거

ORD 기록: ord-7553bb3070734e0794e8ab195e60032b
출처 데이터셋: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08980911B2

반응 노트

불러오는 중…