N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide → 4-{[7-(Acetylamino)-1H-pyrrolo[2,3-c]pyridin-3-yl]carbonyl}-3,5-dichloro-N-ethylbenzamide
반응식
[NH:1]1[C:5]2=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:14][C:15]1[CH:20]=[C:19]([C:21](=[O:25])[NH:22][CH2:23][CH3:24])[CH:18]=[C:17]([Cl:26])[C:16]=1[C:27](Cl)=[O:28]>>[C:11]([NH:10][C:6]1[N:7]=[CH:8][CH:9]=[C:4]2[C:3]([C:27]([C:16]3[C:17]([Cl:26])=[CH:18][C:19]([C:21]([NH:22][CH2:23][CH3:24])=[O:25])=[CH:20][C:15]=3[Cl:14])=[O:28])=[CH:2][NH:1][C:5]=12)(=[O:13])[CH3:12]참가 물질
3
실험 절차
4-{[7-(Acetylamino)-1H-pyrrolo[2,3-c]pyridin-3-yl]carbonyl}-3,5-dichloro-N-ethylbenzamide was prepared from N-(1H-pyrrolo[2,3-c]pyridin-7-yl) acetamide and 2,6-dichloro-4-(ethylcarbamoyl)benzene carbonyl chloride (Compound No. 9).
출처 및 근거
- ORD 기록
- ord-9098f6f4c3db4584bed40b32174cb4fb
- 출처 데이터셋
- uspto-grants-2015_03