6-Azaindole → 3,5-Dichloro-N-(2-methoxyethyl)-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide

HRID 875429노트

반응식

HRID 875429 반응식
[NH:1]1[C:5]2=[CH:6][N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:10][C:11]1[CH:16]=[C:15]([C:17](=[O:23])[NH:18][CH2:19][CH2:20][O:21][CH3:22])[CH:14]=[C:13]([Cl:24])[C:12]=1[C:25](Cl)=[O:26]>>[Cl:10][C:11]1[CH:16]=[C:15]([CH:14]=[C:13]([Cl:24])[C:12]=1[C:25]([C:3]1[C:4]2[C:5](=[CH:6][N:7]=[CH:8][CH:9]=2)[NH:1][CH:2]=1)=[O:26])[C:17]([NH:18][CH2:19][CH2:20][O:21][CH3:22])=[O:23]

참가 물질

3

반응물 2

HCID 92196-AzaindoleHCID 867206362,6-Dichloro-4-(2-methoxyethylcarbamoyl)benzene carbonyl chloride

생성물 1

HCID 716183023,5-Dichloro-N-(2-methoxyethyl)-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide

실험 절차

3,5-Dichloro-N-(2-methoxyethyl)-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide was prepared from 1H-Pyrrolo[2,3-c]pyridine and 2,6-dichloro-4-(2-methoxyethylcarbamoyl)benzene carbonyl chloride (Compound No. 14).

출처 및 근거

ORD 기록
ord-8dfc5fb86e8547adb72812ddf219217c
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08980911B2

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