2-Chloro-3,6-difluorobenzoyl chloride → N-[3-(2-chloro-3,6-difluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide
반응식
[NH:1]1[C:5]2=[CH:6][N:7]=[C:8]([NH:10][C:11]([CH:13]3[CH2:15][CH2:14]3)=[O:12])[CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:16][C:17]1[C:25]([F:26])=[CH:24][CH:23]=[C:22]([F:27])[C:18]=1[C:19](Cl)=[O:20]>>[Cl:16][C:17]1[C:25]([F:26])=[CH:24][CH:23]=[C:22]([F:27])[C:18]=1[C:19]([C:3]1[C:4]2[C:9](=[C:8]([NH:10][C:11]([CH:13]3[CH2:15][CH2:14]3)=[O:12])[N:7]=[CH:6][CH:5]=2)[NH:1][CH:2]=1)=[O:20]참가 물질
3
실험 절차
N-[3-(2-Chloro-3,6-difluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide was prepared using N-(1H-pyrrolo[2,3-c]pyridin-5-yl)cyclopropane carboxamide and 2-chloro-3,6-difluorobenzoyl chloride (Compound No. 37).
출처 및 근거
- ORD 기록
- ord-1cb666f9051b47899f0e26f29a3a0a44
- 출처 데이터셋
- uspto-grants-2015_03