HCID 71061827, 화합물 → N-[1-(2,6-dichlorobenzoyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]cyclopropanecarboxamide
반응식
[Cl:1][C:2]1[CH:24]=[C:23](C#N)[CH:22]=[C:21]([Cl:27])[C:3]=1[C:4]([N:6]1[C:14]2[CH:13]=[C:12]([NH:15][C:16]([CH:18]3[CH2:20][CH2:19]3)=[O:17])[N:11]=[CH:10][C:9]=2[CH:8]=[CH:7]1)=[O:5].N1C2C=C(N(C(C)(CC(C)(C)C)C)C(C3CC3)=O)N=CC=2C=C1.C(C1C=C(Cl)C(C(Cl)=O)=C(Cl)C=1)#N>>[Cl:27][C:21]1[CH:22]=[CH:23][CH:24]=[C:2]([Cl:1])[C:3]=1[C:4]([N:6]1[C:14]2[CH:13]=[C:12]([NH:15][C:16]([CH:18]3[CH2:19][CH2:20]3)=[O:17])[N:11]=[CH:10][C:9]=2[CH:8]=[CH:7]1)=[O:5]참가 물질
4
실험 절차
N-[1-(2,6-dichloro-4-cyanobenzoyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]cyclopropane carboxamide (Compound No. 137) was prepared from N-(1H-pyrrolo[3,2-c]pyridin-6-yl)-N-(2,4,4-trimethylpentan-2-yl)cyclopropane carboxamide by treating with 4-cyano-2,6-dichlorobenzoyl chloride following a procedure as per step k and l in Example 27.