Boronic acid, (4-ethylphenyl)- → HCID 66701325, 화합물

HRID 876226노트

반응식

HRID 876226 반응식
Br[C:2]1[CH:3]=[C:4]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:9])[CH:5]=[N:6][CH:7]=1.[CH2:17]([C:19]1[CH:24]=[CH:23][C:22](B(O)O)=[CH:21][CH:20]=1)[CH3:18]>>[CH2:17]([C:19]1[CH:24]=[CH:23][C:22]([C:2]2[CH:3]=[C:4]([C:8]([NH:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[O:9])[CH:5]=[N:6][CH:7]=2)=[CH:21][CH:20]=1)[CH3:18]

참가 물질

3

반응물 2

HCID 2734352Boronic acid, (4-ethylphenyl)-HCID 42730445-BROMO-N-PHENYLNICOTINAMIDE

생성물 1

HCID 66701325HCID 66701325, 화합물

실험 절차

74 g (222 mmol) of 5-bromo-N-phenylpyridine-3-carboxamide and 40 g (266 mmol, 1.2 eq.) of 4-ethylphenylboronic acid were reacted according to General Method 1A. Yield: 68 g (87% of theory)

출처 및 근거

ORD 기록
ord-1d717933e4774ee8aa82d1a3bcaccfb3
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987248B2

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