Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbamic chloride, N-methyl-N-phenyl- → 3-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-methyl-1-phenylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbamic chloride, N-methyl-N-phenyl- | HCID 77969 | — |
| 반응물 | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate | HCID 66701344 | — |
| 생성물 | 3-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-methyl-1-phenylurea | HCID 46931633 | — |
반응 단계
60 mg (0.14 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 22 mg (0.14 mmol, 1.0 eq.) of methyl(phenyl)carbamoyl chloride were reacted according to General Method 3. Yield: 37 mg (69% of theory)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987248B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-de69b6571ad644d186feca8e15691b68 |
| 출처 메모 | uspto-grants-2015_03 |