Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylsulfonic acid → N-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-phenylmethanesulphonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylsulfonic acid | HCID 7532 | — |
| 반응물 | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate | HCID 66701344 | — |
| 생성물 | N-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-phenylmethanesulphonamide | HCID 46931630 | — |
반응 단계
55 mg (0.12 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 7A) and 21 mg (0.11 mmol, 0.9 eq.) of phenylmethanesulphonic acid were reacted according to General Method 6. Yield: 14 mg (24% of theory)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987248B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-3229bcb1d7d4441dae8dc3f88b35e51f |
| 출처 메모 | uspto-grants-2015_03 |