tert-butyl N-(6-aminoisoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate → (2R)-2-hydroxy-N-[4-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]-2-[(2R)-3-oxo-4-[4-(trifluoromethoxy)phenyl]morpholin-2-yl]acetamide

반응식

[OH:1][C@H:2]([C@H:6]1[O:11][CH2:10][CH2:9][N:8]([C:12]2[CH:17]=[CH:16][C:15]([O:18][C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=2)[C:7]1=[O:23])[C:3]([OH:5])=O.[NH2:24][C:25]1[CH:30]=[CH:29][C:28]([C:31]2[NH:32][O:33][C:34](=[O:36])[N:35]=2)=[CH:27][CH:26]=1.NC1C=C2C(=CC=1)C(N(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)=NC=C2>CN(C=O)C>[OH:1][C@H:2]([C@H:6]1[O:11][CH2:10][CH2:9][N:8]([C:12]2[CH:17]=[CH:16][C:15]([O:18][C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=2)[C:7]1=[O:23])[C:3]([NH:24][C:25]1[CH:26]=[CH:27][C:28]([C:31]2[NH:35][C:34](=[O:36])[O:33][N:32]=2)=[CH:29][CH:30]=1)=[O:5]