Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 7-Nitroquinazolin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 4-Chloro-7-nitroquinazoline | HCID 830680 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 7-Nitroquinazolin-4-amine | HCID 13697798 | — |
반응 단계
A mixture of 1.6 g of 4-chloro-7-nitroquinazoline in 50 ml 7N ammonia in methanol was stirred overnight at rt and concentrated to dryness. The solid was suspended in water, filtered, rinsed with water followed by ether and dried overnight in vacuum oven to provide 0.98 g of 7-nitroquinazolin-4-amine (compound 98-2).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987242B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-1bcd3184a8ff4d60b219145e85c3fa70 |
| 출처 메모 | uspto-grants-2015_03 |