Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → HCID 67306428, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 4,5,6,7-Tetrahydrothieno(3,2-c)pyridinium chloride | HCID 10176342 | — |
| 반응물 | HCID 58514601 | HCID 58514601 | — |
| 생성물 | HCID 67306428 | HCID 67306428 | — |
반응 단계
The mixture 6-((5-chloro-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)methyl)quinoline (60 mg, 0.2 mmol) (prepared according to Compound 60), Cs2CO3 (195 mg, 0.6 mmol) and 4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (52 mg, 0.3 mmol) in DMF (1.5 mL) was stirred at 120° C. overnight, then concentrated. The residue was purified by chromatography to afford the title compound MS (m/z): 399 (M+1)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987269B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-c691621327fa4afd895c94af5d641f9c |
| 출처 메모 | uspto-grants-2015_03 |