Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(5-Chloro-2-methylphenyl)boronic acid → N-[4-(5-chloro-2-methyl-phenyl)-pyridin-3-yl]-2,2-dimethyl-propionamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (5-Chloro-2-methylphenyl)boronic acid | HCID 2773336 | — |
| 반응물 | N-(4-Iodopyridin-3-yl)-2,2-dimethylpropanamide | HCID 10447729 | — |
| 용매 | Ethylacetate heptane | HCID 21899848 | — |
| 생성물 | N-[4-(5-chloro-2-methyl-phenyl)-pyridin-3-yl]-2,2-dimethyl-propionamide | HCID 70663288 | — |
반응 단계
The title compound was prepared in analogy to example 72, from N-(4-iodo-pyridin-3-yl)-2,2-dimethyl-propionamide (CAS RN 113975-32-9) and 5-chloro-2-methylphenylboronic acid (CAS RN 148839-33-2) and using a gradient of n-heptane:EtOAc (100:0 to 0:100). Light yellow solid (99%). MS (ESI): m/z=303.126 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987307B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-d620593104e74924b11517bf91f926ed |
| 출처 메모 | uspto-grants-2015_03 |