5-Bromo-2-thiophenesulfonamide → 5-[5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

HRID 87830노트

반응식

HRID 87830 반응식
[Br:23][c:24]1[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]1.[Cl:1][c:2]1[c:3]([CH3:22])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]([F:15])[F:16])[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[CH:21])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([CH3:22])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]([F:15])[F:16])[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[C:21][c:24]2[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]2)[cH:6][cH:7]1

참가 물질

3

반응물 2

HCID 12413045-Bromo-2-thiophenesulfonamideHCID 866080845-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-3-ethynyl-pyrazolo[1,5-a]pyrimidine

생성물 1

HCID 118526185-[5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

출처 및 근거

ORD 기록
ord-bceadddc89ea49459271fd0e90e1bb51
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

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