Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylboronic Acid → 2-Chloro-6-phenylpyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylboronic Acid | HCID 66827 | — |
| 반응물 | 2,6-Dichloropyrazine | HCID 78504 | — |
| 생성물 | 2-Chloro-6-phenylpyrazine | HCID 5216092 | — |
반응 단계
Prepared from 2,6-dichloropyrazine (1.01 g, 6.78 mmol) and phenylboronic acid (946.7 mg, 7.76 mmol) according to Method K, except the product was purified by silica gel chromatography (DCM, Rf=0.37) instead of preparative HPLC: 1H NMR (300 MHz, chloroform-D) δ ppm 7.46-7.53 (m, 3H), 7.94-7.98 (m, 2H), 8.22 (s, 1H), 8.63 (s, 1H). MS (DCI/NH3) m/z=191 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987453B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-897a0f18debb4261b231167c27d39f23 |
| 출처 메모 | uspto-grants-2015_03 |