Dichlorobenzyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

HRID 878949

반응식

HRID 878949 반응식
[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4]Cl.[CH2:11]([N:18]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=2)[CH:20]=[CH:19]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][N:18]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=2)[CH:20]=[CH:19]1.[CH2:11]([N:18]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=2)[CH:20]=[CH:19]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

참가 물질

4

반응물 2

HCID 76790Dichlorobenzyl chlorideHCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acid

생성물 2

HCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acidHCID 68183775HCID 68183775, 화합물

실험 절차

The titled compound (13 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2,3-dichlorobenzyl chloride according to the method of the process (7) of Example 4.

출처 및 근거

ORD 기록
ord-89a09d82c2884ce2861948c30ab3d604
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987473B2

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