2-(Chloromethyl)naphthalene → 2-(1-benzyl-1H-indole-6-yl)acetic acid

HRID 878970

반응식

HRID 878970 반응식
Cl[CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[CH2:13]([N:20]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([CH2:29][C:30]([OH:32])=[O:31])[CH:27]=2)[CH:22]=[CH:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[CH:12][C:3]=1[CH2:2][N:20]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([CH2:29][C:30]([OH:32])=[O:31])[CH:27]=2)[CH:22]=[CH:21]1.[CH2:13]([N:20]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([CH2:29][C:30]([OH:32])=[O:31])[CH:27]=2)[CH:22]=[CH:21]1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

4

반응물 2

HCID 756322-(Chloromethyl)naphthaleneHCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acid

생성물 2

HCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acidHCID 681844892-[1-(Naphthalene-2-ylmethyl)-1H-indole-6-yl]acetic acid

실험 절차

The titled compound (31 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-(chloromethyl)naphthalene according to the method of the process (7) of Example 4.

출처 및 근거

ORD 기록
ord-a8623b45047e42609586230d725c3f4d
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987473B2

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